The effect of combined training on level of immune factors in HIV-infected patients

Authors
Abbass katanchi
Masoud Hajrasouli
Laleh Behboodi
Department of Physical Education and Sport Science, Islamshahr Branch, Islamic Azad University, Iran
Abstract
Introduction

Acquired immune deficiency syndrome (AIDS) is associated with abnormalities in the functioning of the human immune system. The aim of this study was to investigate the effect of combined training on level of immune factors in HIV-infected patients.

Materials and Methods

In this semi-experimental study, 30 male patients with AIDS were targeted and accessible selected and randomly divided into two groups; combined training and control. The combined training program was run for 12 weeks and 3 sessions per week. Aerobic training involves walking or jogging on the treadmill with rising intensity and duration of 40% to 65% of maximum heart rate and a duration of 30 -60 minutes. Also, Strength training includes 2 to 4 sets and 12 to 20 repetitions per isotonic device in the range of 40% to 60% 1RM. 24 hours before and 72 hours after intervention, blood samples were retested. CD4 lymphocytes and Viral Load levels measured by flow cytometry. Data were analyzed by independent t-test at the P <0.05.

Results

The results showed that 12 weeks of the combined exercise was associated with a nonsignificant increase in CD4 levels in patients with acquired immunodeficiency (AIDS) (p=0.461). Combined exercise had no significant effect on serum viral load in patients with acquired immunodeficiency (AIDS) (p=0.926).

Conclusion

According to the results of the study, there was a slight increase in CD4 count in the exercise group but this value was not significant. However, it was clinically valuable. Therefore, combined training can be performed safely and effectively in these patients.
Keywords
Combined training
human immune system
CD4
Viral load
AIDS
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Journal of Netshabur University of Medical Sciences
Volume 8, Issue 3 - Serial Number 28
Autumn 2020
Pages 108-117