Different Aspects of Mallow (Malva sylvestris) and Results of New Research Findings: A Review

Authors
Abstract
Introduction and Aims

Malva (Malva sylvestris L.) is member of the Malvaceae family, native to Iran, which used as food and medicine to treat many disorders in traditional medicine. The present article has reviewed different aspects and new finding about this medicinal plant.

Materials and Methods

In this study using Iranmedex, Sid, Web of Science and Science Direct databases, articles on various aspects of mallow was reviewed, with using keywords: “malva” and “pharmacological effect”, and “medical plant”.

Results

In traditional medicine, M.sylvestris has been used in pain relief, inflammation, wound healing and treatment of kidney disorders, skin problems and efficacy against microorganisms such as viruses, bacteria. Arial parts of this plant are highly valuable for animal feeding. Antioxidant properties of Malva are due to delfinidin, malvidin, beta-carotene, cyanine, tannins, saponins, alkaloids, mucilage and phenolic and flavonoid components.

Conclusion

Traditional applications of M.sylvestris in treatment of many diseases and its valuable medicinal and herbal components could provide a context for scientists to develop plant-derived medications such as antibiotics, sedatives and inflammation treating drugs.



* Corresponding Author: Agriculture Sciences and Natural Resources University of Gorgan, Range Management Faculty.

Email: Shokrollahi.sh93@yahoo.com
Keywords

Kafash Farkhad N, Asadi Samani M, Khaledifar B. A review on secondary metabolites and pharmacological effects of Prangos ferulacea (L.) Lindl. Iranian J Shahrekord Univ Med Sci. 2013;15(3):98-108. [Persian]

Asadi Samani M, Rafieian Kopaei M, Azimi N. Gundelia: a systematic review of medicinal and molecular perspective. Pak J Biol Sci. 2013;16(21):1238-47. [Persian]

Henry AG, Piperno DR. Using plant microfossils from dental calculus to recover human diet: a case study from Tell al-Raqa’i, Syria. J Archaeol Sci. 2008; 35:1943-50.

Riedl I, Malvaceae. In: Rechinger, KH, editor. Flora Iranica. Graz: Akad. Druck- und Verlag-Anst; 1976.

Pakravan M. New findings of the genus Malva L. (Malvaceae) in Iran. Iranian Journal of Botany, 2006;11(2):247-9. [Persian]

Lust J. The Herb Book: The Most Complete Catalog of Herbs Ever Published. 1st ed. Toronto: Courier Corporation; 1974.

Tabaraki R, Yosefi Z, Asadi GHarneh H A. Chemical Composition and Antioxidant Properties of Malva sylvestris L. J Agric Res. 2012;8(1):59-68.

Scherrer AM, Motti R, Weckerle CS. Traditional plant use in the areas of Monte Vesole and Ascea, Cilento National Park (Campania, Southern Italy). J Ethnopharmacol. 2005;97(1):129-43.

Kültür S. Medicinal plants used in Kirklareli province (Turkey). J Ethnopharmacol. 2007;111(2):341-64.

Mustafa A, Ali M. New steroidal lactones and homomonoterpenic glucoside from fruits of Malva sylvestris L. J Acta Pol Pharm. 2011;68(3):393-401.

Taha Nezhad M, Barzegar M, Sahari MA, Naghdi Badi HA. Evaluating antiradical activity of Mallow (Malva sylvestris L.) extracts and its application in the oil system. Iranian J of Med Plants. 2012;11(42):86-97. [Persian]

Arzi A, Nazari Khorasgani Z, Rahmani M. Study the effects of Malva sylvestris hydro-alcoholic extract on carrageenan-induced inflammation in male rat paw. Jentashapir, 2013;4(1):1-10. [Persian]

Mohammad Eini A, Shayegh J, Moharrami fard M. Comparison of Antibacterial Effect of Malva Sylvestris L. (Aerial and Root Organs) by MIC. J Shaheed Sadoughi Univ Med Sci. 2014;21(6):816-22. [Persian]

Basaran D, Ahmet G. Antimicrobial activity of certain plants used in Turkish traditional medicine. Asian J Plant Sci. 2004;3(1):104-7. [Persian]

Cleverson Gasparettoa J, Ferreira Martinsa CA, Hayashia SS, Fleith Otukyb M, Pontaroloa R. Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine. J Pharm Pharmacol. 2012;64(2):172-89.

Marouane W, Soussi A, Murat J, Bezzine S, El Feki, A. The protective effect of Malva sylvestris on rat kidney damaged by vanadium. J Lipids Health Dis. 2011;10:65-70.

Razavi M, Zarrini G, Molavi G, Ghasemi G. Bioactivity of malva sylvestris L., a medicinal plant from Iran. Iran J Basic Med Sci. 2011;14(6):574-9.

Shale TL, Stirk WA, van Staden J. Variation in .antibacterial and anti .inflammatory activity of different growth forms of Malva parviflora and.evidence for synergism of the anti-inflammatory compounds. J Ethnopharmacol. 2005:96(1-2):325-30. [Persian]

Hicsonmez U, Erees FS, Ozdemir C, Ozdemir A, Cam S. Determination of major and minor elements in the Malva sylvestris L. from Turkey using ICP-OES techniques. Biol Trace Elem Res. 2009;128(3):248-57.

Classen B, Blaschek W. High molecular weight acidic polysaccharides from Malva sylvestris and Alcea rosea. Planta Med. 1998;64(7):640-4.

Noohizadeh Z, Parivar K, Hayati Roudbari N. The effect of mallow (Malva sylvestris) leaves on sperm and spermatogenesis in mice C-57. ‎Anim Biol. 2015;7(2):81-8. [Persian]

Ghassemi Dehkordi N, Sajjadi SE, Ghannadi A, Amanzadeh Y, Azadbakht M, Asghari GR. Iranian Herbal Pharmacopoeia. Hakim Res J. 2003;6(3):11-20. [Persian]

Emad M, Gheibi F, Rasooli M, Khanjanzadeh R, Jozani S. [Medicinal-industrial plant: Mallow. Malva sylvestris L]. 1st ed. Tehran: Peyman No Andish; 2012, 48. [Persian]

Najafi Momen R, Torabi Goodarzi M. A case report of poisoning with Common Mallow (Malva neglecta wallr) in a Milking Cow. Vet Res. 2005;60(4):405-6. [Persian]

Barros L, Carvalho AM, Ferreira IC. Leaves, flowers, immature fruits and leafy flowered stems of Malva sylvestris: A comparative study of the nutraceutical potential and composition. Food Chem Toxicol. 2010;48(6):1466-72.

Farina A, Doldo A, Cotichini V, Rajevic M, Quaglia MG, Mulinacci N, et al. HPTLC and reflectance mode densitometry of anthocyanins in Malva silvestris L. a comparison with gradient-elution reversed-phase HPLC. J Pharm Biomed Anal. 1995;14(1-2):203-11.

Zargari A. [Medicinal plants]. 5th ed. Tehran: Tehran University; 1995, 34-8. [Persian]

Zhen-Yu W. Impact of anthocyanin from Malva sylvestris on plasma lipids and free radical. J For Res. 2005;16(3):228-32.

Eloff JN. Which extractant should be used for the screening and isolation of antimicrobial components from plants?. J Ethnopharmacol. 1998:60(1):1-8.

Tahoori H. [Encyclopedia of Medicinal Plants]. 9th ed. Qom: Padide Danesh; 2004, 520. [Persian]

Pirbalouti AG, Azizi S, Koohpayeh A, Hamedi B. Wound healing activity of Malva sylvestris and Punica granatum in alloxan-induced diabetic rats. Acta Pol Pharm. 2010;67(5):511-6. [Persian]