Comparison of the Effect of Resistance Training Periods With and Without Blood Flow Restriction on Changes in Plasma Levels of Creatine Kinase and Lactate Dehydrogenase Enzymes in Active Boys

Author
abolfazl torabi
Abstract
Introduction: A consequence of high-intensity resistance training is muscle damage. The aim of this study was to compare the effect of a resistance training period with and without blood flow restriction on physical fitness factors and plasma creatine kinase and lactate dehydrogenase enzyme levels in active boys.

Methods: for this study, 24 active adolescent boys (mean weight 68.15±4.21 kg and mean age 16.52±0.62 years) were familiarized with bodybuilding equipment and then divided into 3 groups of 8: resistance exercise with blood flow restriction and exercise intensity of 30% 1RM, resistance exercise without blood flow restriction and exercise intensity of 75% 1RM and control group. The training program lasted for 6 weeks, with three sessions per week. Before and after 6 weeks of resistance training with and without blood flow restriction, plasma creatine kinase and lactate levels were measured. The exercise training protocol was based on free weight, with the participants performing two upper and three lower body movements per session. Each movement consisting of 3 sets and 10 repetitions, with 2 minutes intraset rest period and 5 minutes interset rest period. Special cuffs were used to restrict blood flow. A one-way ANOVA was used to test the hypotheses, and LSD post-hoc tests were used to identify specific differences if a significant difference was found.

Results: The findings showed that resistance training with blood flow restriction led to a significant decrease in the plasma levels of creatine kinase (p=0.01) compared with the resistance training group without blood flow restriction and control groups. However, the plasma levels of lactate dehydrogenase showed no significant difference between the groups (p=0.56, p=0.53).

Conclusion: It appears that resistance training with blood flow restriction can be considered a preventive approach for muscle damage in active boys.
Keywords
Resistance exercise with blood flow restriction on delayed contusion indices
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