Comparison of the Effect of Ropivacaine and Bupivacaine, on Hemodynamic Changes in Patients Undergoing Nephrolithotripsy Surgery under Spinal Anesthesia

Authors
Fatemeh Eftekharian
Ahmad Rastgarian
Reza Inaloo
Reza Sahraei
Abstract
Introduction: Postoperativeanalgesia and immobility are among the most important issues that significantly impact surgical outcomes and surgeon satisfaction. Therefore, the purpose of this study was to compare the effects of ropivacaine and bupivacaine on the extent of hemodynamic changes in patients undergoing nephrolithotripsy surgery with spinal anesthesia.

Methods: This study is a double-blind randomized clinical trial. In total, 93 patients who underwent nephrolithotripsy surgery with anesthesia classes 1 and 2 were included in the study. Patients were randomly divided into two groups: bupivacaine and ropivacaine. The data collection tool in this study included a checklist containing information; Age, gender, systolic, and diastolic blood pressure, heart rate and arterial blood oxygen saturation percentage.

Results: The results of the present study showed that the bupivacaine and ropivacaine groups were similar in terms of gender. The results of Ozone's t-test showed that there was no statistically significant difference between the bupivacaine and ropivacaine groups in terms of systolic and diastolic blood pressure, shortness of breath. There was a significant difference between bupivacaine and ropivacaine groups in the heart rate in ten minutes (P=0.038). However, no significant difference was observed between the two groups at other time points. The average heart rate in 10 min was higherin the ropivacaine group than in the bupivacaine group.

Conclusion: The results of the present study indicated no statistically significant difference between the ropivacaine and bupivacaine groups regarding the number of hemodynamic changes in patients undergoing nephrolithotripsy surgery with spinal anesthesia. Further studies with higher sample sizes and higher doses.
Keywords
Bupivacaine
Ropivacaine
Nephrolithotripsy
Hemodynamic
Spinal
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