Investigation of cutaneous leishmaniasis in Hamidieh County in 2016-2020

Authors
elham jahanifard
elham maraghi
zahra mousavi
shahla bigdeli
Abstract
Introduction: Considering the importance of cutaneous leishmaniasis in Iran and Khuzestan province, a study was designed to investigate the frequency, incidence, and distribution of cutaneous leishmaniasis in Hamidieh County from 2016-2020.

Methods: In this retrospective study, the recorded information of the affected patients was collected over the years in Hamidieh County and analyzed using SPSS software version 26.

Results: Out of 128 patients identified in Hamidieh County during the considered years, 80 (%62.5) were men, and 48 (%37.5) were women, with an average age of 21.01 years. The most cases were reported in autumn and winter and the least were reported in spring. A total of 93 people (%72.7) were rural residents and the rest were urban residents. In terms of occupation, the most affected people (not including children) were military personnel with 24 cases (%25.8) and the least related to drivers and other occupations with 2 cases (%2.2). Among the affected people, 8 people (%6.3) had a history of traveling to endemic areas. Approximately, 57 people (%44.5) had one wound, and the hand was the most involved organ. The lowest and highest incidence rates were 5.98 and 2.34 per 10000 people, respectively in 2017 and 2018. Among the areas, the Hamidiyeh and Saman Al-Aima barracks have had disease reports throughout the years.

Conclusion: The incidence of the disease in Hamidieh County has generally decreased, however,basic training is necessary to minimize the incidence.
Keywords
cutaneous leishmaniasis
Hamidiyeh
Incidence
Epidemiology
1. Alvar J, Vélez ID, Bern C, Herrero M, Desjeux P, Cano J, Jannin J, Boer MD. Leishmaniasis Worldwide and Global Estimates of Its Incidence. PLOS ONE 2012;7:e35671.
2. Khademvatan S, Salmanzadeh S, Foroutan-Rad M, Bigdeli S, Hedayati-Rad F, Saki J, Heydari-Gorji E. Spatial distribution and epidemiological features of cutaneous leishmaniasis in southwest of Iran. Alexandria J Med. 2017; 53(1):93-8.
3. Ghatee MA, Taylor WR, Karamian M. The geographical distribution of cutaneous leishmaniasis causative agents in Iran and its neighboring countries, a review. Public Health Front. 2020; 8:11.
4. Yaghoobi-Ershadi MR. Phlebotomine sand flies (Diptera: Psychodidae) in Iran and their role on Leishmania transmission. J Arthropod Borne Dis. 2012; 6(1):1-17.
5. -Karimi A, Jahanifard E, Abai MR, Rassi Y, Veysi A, Hanafi-Bojd AA, Hosseini M, Saeidi Z, Tavakoli M, Maleki M, Jafari R. Epidemiological survey on Cutaneous Leishmaniasis in southwestern Iran. J. Vector Borne Dis. 2020; 57(2): 121-127.
6. -Vazirianzadeh B, Saki J, Jahanifard E, Zarean M, Amraee K, Pour SN. Isolation and Identification of Leishmania Species From Sandflies and Rodents Collected From Roffaye District, Khuzestan Province, Southwest of Iran. JJM. 2013; 6(6): e10025.
7. Foroutan M, Khademvatan S, Majidiani H, Khalkhali H, Hedayati-Rad F, Khashaveh S, Mohammadzadeh H. Prevalence of Leishmania species in rodents: a systematic review and meta-analysis in Iran. Acta Trop. 2017; 172:164-72.
8. Alvar J, Vélez ID, Bern C, Herrero M, Desjeux P, Cano J, Jannin J, Boer MD, WHO Leishmaniasis Control Team. Leishmaniasis worldwide and global estimates of its incidence. PloS one. 2012; 7(5): e35671.
9. Sabzevari S, Teshnizi SH, Shokri A, Bahrami F, Kouhestani F. Cutaneous leishmaniasis in Iran: a systematic review and meta-analysis. Microb Pathog. 2021; 152:104721.
10. Nasiri Z, Kalantari M, Mohammadi J, Daliri S, Mehrabani D, Azizi K. Cutaneous leishmaniasis in Iran: A review of epidemiological aspects, with emphasis on molecular findings. Parasite. 2022; 29:47.
11. Nejati J, Mojadam M, Hanafi Bojd AA, Keyhani A, Habibi Nodeh F. An epidemiological study of cutaneous leishmaniasis in Andimeshk (2005-2010). J Ilam Univ Med Sci. 2014; 21(7): 94-101. [Persian]
12. Behbahani A, Ahmadi S, Latifi SM, Sadeghi M. Study of the frequency of Cutaneous Leishmaniasis in Omidieh district, Khouzestan province, south west of Iran (2008-2010). JJHS. 2012; 4(4): 37-46. [Persian]
13. Ostad M, Shirian S, Pishro F, Abbasi T, Ai A, Azimi F. Control of cutaneous leishmaniasis using geographic information systems from 2010 to 2014 in Khuzestan Province, Iran. PloS one. 2016; 11(7):e0159546.
14. Chenani-Rahimi K, Maleki M, Behbahani A. Cutaneous Leishmaniasis Analyses in an Endemic Focus in Southwest Iran (2016-2020). Dis Diagn. 2022; 11(4):137-41.
15. Jahanifard E, Hanafi-Bojd AA, Nasiri H, Matinfar HR, Charrahy Z, Abai MR, Yaghoobi-Ershadi MR, Akhavan AA. Prone regions of zoonotic cutaneous leishmaniasis in southwest of Iran: combination of hierarchical decision model (AHP) and GIS. J Arthropod Borne Dis. 2019; 13(3):310-323.
16. Rassa SF, Maraghi E, Bigdeli S, Jahanifard E, Behnampour Z, Nasiri Z. Demographic study of cutaneous leishmaniasis and its geographical distribution in Dasht-e Azadegan County (2014-2018). Sci Med J Ahwaz Jundishapur Univ Med Sci. 2020; 19(2): 215-25.[Persian]
17. Salname Amari. Iran: Statistical Center of Iran, Office of the Head, Public Relations and International Cooperation. 2018: 935 pages.
18. Nazari M. Cutaneous leishmaniasis in Hamadan, Iran (2004-2010). Zahedan J Res Med Sci. 2012; 13(9).[Persian]
19. Jorjani O, Kamalinia HR, Mehrbakhsh Z, Ziaei-Hezarjaribi H, Pourrostami K, Mansourian M, Safari O, Abedzadeh Zavareh M S, Mirkarimi K. Pediatric Cutaneous Leishmaniasis in Golestan Province, Iran: A Cross-Sectional Study of 8-years. Int. J. Pediatr, 2019; 7(8): 9831-9839.
20. Soltani S, Foroutan M, Hezarian M, Afshari H, Kahvaz MS. Cutaneous leishmaniasis: an epidemiological study in southwest of Iran. J Parasit Dis. 2019; 43(2):190-7.
21. Islamic Republic of Iran Ministry of Health and Medical Education. [Instruction of leishmaniasis control] Persian. Tehran: Center for disease control; 1999: 68.
22. Parasites –Leishmaniasis. Centers for Disease Control and Prevention. Available at: URL: https://www.cdc.gov/parasites/leishmaniasis/prevent.html#:~:text=Minimize%20the%20amount%20of%20exposed,wearing%20insecticide%2Dtreated%20clothing. (Accessed: February 14, 2020)
23. Doroodgar A, Mahbobi S, Nemetian M, Sayyah M, Doroodgar M. An epidemiological study of cutaneous leishmaniasis in Kashan (2007-2008). Koomesh. 2009; 10(3).[Persian]
24. Hamzavi Y, Khademi N. Trend of cutaneous leishmaniasis in kermanshah province, west of iran from 1990 to 2012. Iran J Parasitol. 2015 Jan-Mar;10(1):78-86.
25. Haghshenas H, Akbari H, Nowrouzi M, Mehralizadeh A, Haghighat GA. Investigation of the Epidemiological Trend of Cutaneous Leishmaniasis in Patients Referring to the Division of Health Center of Gerash (South of Fars Province) during 2007-2020. J Health Res Commun. 2021; 7(4):39-47.[Persian]
26. Mohammadi Azni S, Nokandeh Z, Khorsandi AA, AR SD. Epidemiology of cutaneous leishmaniasis in Damghan district. Journal Mil Med. 2010 Oct 19;12(3):131-5.[Persian]
27. Nilforoushzadeh MA, Shirani-Bidabadi L, Hosseini SM, Fadaei-Nobari R, Jaffary F. The epidemiology of cutaneous leishmaniasis in Isfahan province, Iran, during 2001-2011. J Isfahan Med Sch. 2015; 32(315):2241-51.[Persian]
28. Sofizadeh A, Cherabin M, Mehravaran A. Cutaneous leishmaniasis in Gonbad Kavoos, North of Iran (2009-11): an epidemiological study. J Gorgan Univ Med Sci. 2013; 14(4):100-6. [Persian]
29. Razavi MR, Shirzadi MR, Mohebali M, Yaghoobi-Ershadi MR, Vatandoost H, Shirzadi M, Gouya MM, Gharachorloo F, Arshi S, Amiri B. Human Cutaneous Leishmaniosis in Iran, Up to Date-2019. J Arthropod Borne Dis. 2022; 15(2):143-151.
30. Moghateli M, Atesh BF, Yoshany N, Movahed E, Jadgal KM, Izadirad H, Fattahi BA. Incidence rate of cutaneous leishmaniasis in Chabahar within 2008-2010. JCHR. 2016; 5(1): 29-35. 31. Hatami I, Khanjani N, Aliakbarpoor M, Dehghan A. Epidemiologic characteristics and time trend of cutaneous leishmaniasis incidence in cities under the surveillance of Shiraz University of Medical Sciences. J Sch Public Health Inst Public Health Res. 2018; 16(1).[Persian]
32.Khajedaluee M, Yazdanpanah MJ, Seyed Nozadi SM, Fata A,Juya MR, Masoudi MH, Najaf Najafi M. Epidemiology of cutaneous leishmaniasis in Razavi Khorasan in 2011. MJMS. 2014;57: 647-54.[Persian]