The Effect of Anabolic Steroid Boldenone, zizyphus jujube and training on testicular tissue damage in Wistar rats

Authors
majid abbaszadeh 1
hassan matinhomaee 1
parvin farzanegi 2
1 Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
2 Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran
Abstract
Introduction

The use of anabolic-androgenic steroids by athletes has some effects on the structure and function of the organs of the body, such as the genital system. The purpose of this study was to investigate the effect of anabolic steroid Boldenone, endurance and resistance training on testicular tissue damage in Wistar rats

Materials and Methods

77 Wistar rats were randomly divided into the eleven equal groups: control, sham, Boldenone, Gallic acid + Resistance training + Boldenone, Resistance training + Boldenone, Gallic acid + Endurance training + Boldenone, zizyphus jujube + Endurance training + Boldenone, Endurance training + Boldenone, zizyphus jujube + Resistance training + Boldenone, Gallic acid + Boldenone, zizyphus jujube + Boldenone. The resistance exercise protocol consisted of three exercise sessions per week of the climbing ladder for eight weeks, and endurance training for each session 30 minutes at a speed of 12 m / min. Data analysis was performed by two way analysis of variance.

Results

The highest rate of tissue failure and degenerative changes were observed in the Boldenone group. The diameter and size of the Seminiferoustubules are equal and the base membrane is normal in the Boldenone + zizyphus jujube and Boldenone + Resistance training groups. However, the diameter of the tubes was different for each other in the Boldenone+ endurance training group.

Conclusion

Boldonone can damage testicular tissue structure and degenerative changes. It is possible that resistance training with jujube supplementation to endurance training can reduce the testicular tissue damage-induced the boldonone injection.
Keywords
Anabolic Steroid
Resistance and endurance training
Testicular tissue
rat
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Journal of Netshabur University of Medical Sciences
Volume 7, Issue 1 - Serial Number 22
Winter 2019
Pages 144-156