Study of Antibacterial Effect of Salvia officinalis Essence and Comparison with Chlorhexidine on some of Bacterial agents of the Oral Cavity

Authors
Hojjat Eghbal 1
Arezou Mohammadi 2
Nima Mohammad Nejad Khiavi 3
neda Jahani 4
1 Department of Phytochemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran
2 Department of Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Food Science and Technology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran
4 Research & Development, Green Drug Reserchers, Meshkinshahr, Iran
Abstract
Introduction

Salvia officinalis is an herbaceous plant that belongs to the family of Lamiaceae (Labiatae). Salvia officinalis is one of the most important herbal plants used as a disinfectant in traditional and modern medicine. The aim of this research was to study of antibacterial Effect of Salvia officinalis essence and comparison with chlorhexidine on some of the common oral infections of Bacteria.

Materials and Methods

In this research, Salvia officinalis was collected from the Anzan Meshgin-Shahr area in the northwest of Iran. The essential oil was extracted by Clevenger's apparatus, GC and GC/MS devices were used for the analysis of essential oil compounds and accurate measurements of the compounds. Then, the effect of the essential oil of the Salvia officinalis and control on the common bacteria of the oral infection was evaluated in two ways: Disc diffusion And minimum inhibitory concentration (MIC).

Results

According to the results, the essential oil of the herb has a significant inhibitory effect on the types of gram-negative and positive bacteria. Also, comparing the diameter of the non-growth of the plant with chlorhexin, it was found that the essence of the herb medicine showed relatively similar results to that of the chlorhexin.

Conclusion

According to the findings, the essential oil of the herb has a good anti-microbial effect against the common bacteria of oral infections. As a result, the essential oil of this plant with different concentrations, after completing studies, can be an appropriate alternative for chemical drugs and chemical mouthwashes in the treatment of oral bacterial infections.

Keywords
Salvia Officinalis
Essential oil
Oral Bacteria
Antibacterial Agents
Chlorhexidine
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