بررسی روایی و پایایی آزمون کوتاه وضعیت ذهنی در افراد مبتلا به اختلال شناختی خفیف

نویسندگان
دانشگاه علوم پزشکی تبریز
چکیده
مقدمه: این پژوهش با هدف ارزیابی اعتبار و پایایی نسخه فارسی آزمون کوتاه وضعیت ذهنی (MMSE) در جمعیت ایرانی انجام شده است. MMSE یک ابزار رایج برای غربالگری اولیه اختلالات شناختی مانند آلزایمر است. این پژوهش به گسترش دانش در زمینه ارزیابی شناختی در ایران کمک می‌کند و می‌تواند در بهبود تشخیص و درمان اختلالات شناختی در این کشور نقش مهمی ایفا کند.

روش: در این مطالعه، ابتدا نسخه انگلیسی MMSE به فارسی ترجمه و پس از طی مراحل تطبیق فرهنگی، بر روی نمونه‌ای از افراد سالم و مبتلا به آلزایمر و اختلال شناختی خفیف در ایران اجرا شد. سپس ویژگی‌های روان‌سنجی آزمون مانند روایی و پایایی مورد بررسی قرار گرفت.

یافتهها: این مطالعه نشان می‌دهد که نسخه فارسی MMSE یک ابزار معتبر و قابل اعتماد برای غربالگری اولیه اختلالات شناختی در جمعیت ایرانی است و از روایی خوب با اطمینان ۹۵ درصد و پایایی خوب بر پایه ضریب آلفای به دست آمده برای کل آزمون ( 0/85) در جمعیت فارسی زبان دارد.

نتیجهگیری: بر پایه یافتههای پژوهش نسخه فارسی MMSE از پایایی و روایی برخوردار بوده و با استفاده از این آزمون، می‌توان به تشخیص زودهنگام بیماری آلزایمر و سایر اختلالات شناختی کمک کرد و در نتیجه، برنامه‌های درمانی و مراقبتی مناسب‌تری را برای بیماران ارائه نمود.
کلیدواژه‌ها

عنوان مقاله English

Investigating the Validity and Reliability of the Short Mental State Test in People with Mild Cognitive Impairment

نویسندگان English

Jafar Masumi
Maryam Hassanzadeh
چکیده English

Introduction: This study aimed to evaluate the validity and reliability of the Persian version of the Mini-Mental State Examination (MMSE) in the Iranian population. The MMSE is a common tool for early screening of cognitive disorders such as Alzheimer's. This study contributes to the expansion of knowledge in the field of cognitive assessment in Iran and can play an important role in improving the diagnosis and treatment of cognitive disorders in this country.

Methods: In this study, the English version of the MMSE was first translated into Persian, and after cultural adaptation, was administered on a sample of healthy individuals and those with Alzheimer's or mild cognitive impairment in Iran. Then, the psychometric properties of the test such as validity and reliability were determined.

Results: The results showed that the Persian version of the MMSE has sufficient validity and reliability. This test was able to significantly differentiate between healthy individuals and those with Alzheimer's. Also, the results showed a high correlation with other cognitive assessment tools.

Conclusion: This study shows that the Persian version of MMSE is a valid and reliable tool for early screening of cognitive impairment in the Iranian population. Using this test can help in early diagnosis of Alzheimer's disease and other cognitive impairments.

کلیدواژه‌ها English

MMSE
Alzheimer's
Cognitive Impairment
Validation
Iranian Population
1.-Ferri CP, Prince M. Brayne C. Brodaty H. Fratiglioni L. Ganguli M, Hall K, Hasegawa K, Hendrie H, Huang Y, Jorm A, Mathers C, Menezes PR, Rimmer E, Scazufca M; Alzheimer's . Disease International. Global prevalence of dementia: a Delphi consensus study. Lancet. 2005 Dec 17; 366(9503):2112-7.
2. Boustani M. Peterson B. Hanson L. Harris R. Lohr . KN; U.S. Preventive Services Task Force. Screening for dementia in primary care: summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2003 Jun 3; 138(11):927-37.
3. Cummings JL. Mini-Mental State Examination. Norms, normals, and numbers. JAMA. 1993 May 12; 269(18):2420-1.
4. Molloy DW, Alemayehu E, Roberts R. Reliability of a Standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination. Am J Psychiatry. 1991 Jan; 148(1):102-5.
5. Galvin JE, Sadowsky CH. Practical guidelines for the recognition and diagnosis of dementia. The Journal of the American Board of Family Medicine. 2012 May 1;25(3):367-82.
6. Arevalo‐Rodriguez I, Smailagic N, i Figuls MR, Ciapponi A, Sanchez‐Perez E, Giannakou A, Pedraza OL, Cosp XB, Cullum S. Mini‐Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI). Cochrane database of systematic reviews. 2015(3).
7. Pezzotti P, Scalmana S, Mastromattei A, Di Lallo D, " Progetto Alzheimer" Working Group. The accuracy of the MMSE in detecting cognitive impairment when administered by general practitioners: a prospective observational study. BMC Family Practice. 2008 Dec;9:1-1.
8. BABACAN YILDIZ G, UR ÖZÇELİK E, Kolukisa M, TURAN IŞIK A, Gürsoy E, Kocaman G, Celebi A. Validity and Reliability Studies of Modified Mini Mental State Examination (MMSE-I) For Turkish Illiterate Patients with Diagnosis of Alzheimer Disease. Turkish Journal of Psychiatry. 2016 Mar 1;27(1).
9. Cohen L, Manion L, Morrison K. Validity and reliability. InResearch methods in education 2017 Oct 12 (pp. 245-284). Routledge.
10. Monroe T, Carter M. Using the Folstein Mini Mental State Exam (MMSE) to explore methodological issues in cognitive aging research. European Journal of Ageing. 2012 Sep;9:265-74.
11. Baek MJ, Kim K, Park YH, Kim S. The validity and reliability of the mini-mental state examination-2 for detecting mild cognitive impairment and Alzheimer’s disease in a Korean population. PloS one. 2016 Sep 26;11(9):e0163792.
12. Langa KM, Levine DA. The diagnosis and management of mild cognitive impairment: a clinical review. Jama. 2014 Dec 17;312(23):2551-61.
13. Bajaj MK, Sinha UK. Cognitive Deficits and Behavioural Disturbances among Persons with Dementia and their Impact on Caregivers. Amity Journal of Behavioural and Forensic Sciences. 2008;4(1).
14. Chertkow H, Nasreddine Z, Joanette Y, Drolet V, Kirk J, Massoud F, Belleville S, Bergman H. Mild cognitive impairment and cognitive impairment, no dementia: Part A, concept and diagnosis. Alzheimer's & Dementia. 2007 Oct 1;3(4):266-82.
15. Folstein MF, Folstein SE, McHugh PR. "Mini mental state". A practical method for grading the cognitive state of patients for the clinician. Psychiatr Res. 1975 Nov; 12(3):189-98.
16. Blesa R, Pujol M, Aguilar M, Santacruz P, Bertran-Serra I. Hernandez G. Sol JM. Pena Casanova J: NORMACODEM Group. NORMAlisation of Cognitive and Functional Instruments for DEMentia. Clinical validity of the 'mini-mental state" for Spanish speaking communities. Νεuroριychoίοgia. 2001; 39(11):1150-7.
17. Al- Rajeh S, Ogunniyi A, Awada A et al. Preliminary assessment of an Arabic version of the Mini-Mental State Exam. Annals Of Saudi Medicine, 19(2): 1999
18. de Silva HA, Gunatilake SB. Mini Mental State Examination in Sinhalese: sensitive test screen for dementia in Sri Lanka. Int J Geriatr Psychiatry. 2002 Feb; 17(2):134-9.
19. Grigoletto F. Zappala G, Anderson DW, Lebowitz. BD. Norms for the Mini-Mental State Examination in a healthy population. Neurology. 1999 Jul 22; 53(2):315-20.
20. Kabir ZN. Herlitz A. The Bangla adaptation of Mini-Mental State Examination (BAMSE): an instrument to assess cognitive function in illiterate and literate individuals. Int J Geriatr Psychiatry. 2000 May;15(5):441-50.
21. Truong QC, Cervin M, Choo CC, Numbers K, Bentvelzen AC, Kochan NA, Brodaty H, Sachdev PS, Medvedev ON. Examining the validity of the Mini‐Mental State Examination (MMSE) and its domains using network analysis. Psychogeriatrics. 2024 Mar;24(2):259-71.
22. Andersson B, Luo H. The mini-mental state examination in a chinese population: reliability, validity, and measurement invariance. Innovation in Aging. 2023 Dec;7(Suppl 1):385.