مروری بر اثرات زعفران و مواد اولیه آن در بیماری‌های سیستم عصبی

Saffron (Crocus sativus L.), is a small, perennial member of the Iridaceae family, and has been historically utilized as a spice and food flavoring in many different cultures. In addition, saffron has many medicinal effects and pharmacological properties, such as anti-anxiety, antidepressant, anticonvulsant, and anti-Parkinson activities, and has fewer side effects compared to chemical drugs. Several studies have shown that saffron and its active ingredients are as effective in Alzheimer's disease, depression, anxiety, and sleep problems as conventional drugs used in the treatment of these diseases. Although some study results indicate the effects of saffron and its main components on nervous system disorders, however, more studies are needed. On the other hand, the mechanism of these effects in some neurodegenerative disorders has not been determined, although some researchers generally attribute these effects to the antioxidant, anti-inflammatory, and anti-apoptotic properties of saffron and its components. The present study was conducted to facilitate the evaluation of the effects of saffron on nervous system diseases is presented, as well as a review of studies conducted in this field.